
RHR: Why Microglia Are Key to Brain Health, with Dr. Perlmutter
Your brain’s immune cells don’t just react to bad sleep — they listen to your gut, your gums, and your stress. Here’s how microglial priming works and what quiets it.

Your brain’s immune cells don’t just react to bad sleep — they listen to your gut, your gums, and your stress. Here’s how microglial priming works and what quiets it.

A growing body of research links gut-driven inflammation to depressive symptoms — and that changes what actually helps.

If you have depression and digestive issues, the connection isn’t coincidence. Here’s the investigation pathway most doctors never offer.

A spore-forming probiotic strain with real clinical trials showing improvements in depression, anxiety, and gut inflammation.

Your gut inflammation is sending immune signals to your brain. Here’s the cytokine pathway behind depression and anxiety.

Your gut bacteria make a compound called butyrate that crosses into your brain, reduces inflammation, and may be the missing piece in treating depression.

The gut-brain connection is more specific than you think — new research maps the exact pathways your gut bacteria use to influence your mental health.

Your gut bacteria don’t just digest food — they literally control which of your brain genes get expressed.

Your gut bacteria make butyrate from fiber — but not all fiber works the same way. Here’s what to eat, what to skip, and whether supplements are worth it.

A compound your gut bacteria make from fiber literally changes which genes your brain expresses — and the effect compounds over time.

Your gut bacteria produce a compound called butyrate that directly affects brain chemistry. Here is how it works and what you can eat to boost it.

Your gut bacteria produce a compound that literally changes which genes your brain expresses — and it may be the missing piece in understanding depression.
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